CPAP(呼吸机)治疗除了具有消除打鼾及呼吸暂停、改善睡眠质量等及时效果外,还可产生一系列长期效应。
呼吸系统:
白天血氧上升、CO2下降、肺动脉压降低,提高部分患者呼吸中枢的敏感性,增强呼吸肌的收缩力。
心血管系统:
纠正与OSA有关的心律失常及高血压、增加心脏射血量、改善心肌的血供、增强右心功能、降低心血管疾患的死亡率。但CPAP(呼吸机)压力过高可能降低回心血量,在患者有病理性的低血压,如休克、大量应用利尿剂、不能进食、进水时,需严密观察血压及心率的变化。
消化系统:
对合并夜间胃、食管返流者,CPAP(呼吸机)可减少反流的次数而改善症状。
泌尿系统:
可减少OSA患者夜间的小便次数。
血液系统:
可减少OSA患者的红细胞生成、增加血容量,从而降低血红蛋白含量及血液的粘度,故有预防和辅助的治疗心脑血管疾病的作用。
神经精神系统:
OSA患者的记忆力、反应能力、思维能力等部分或全部恢复正常。
内分泌代谢系统:
CPAP(呼吸机)治疗对机体的内分泌代谢系统有广泛的影响,可以使生长激素及男性激素分泌增加,男性患者的性功能改善,肥胖者的体重有所下降。可有提高或改善对胰岛素的敏感性,故有治疗2型糖尿病的作用。
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